Innate Immunity

Question 1

Where are innate immune system receptors encoded, and what does this mean as a result?

Answer 1

Geraldine encoded, = limited diversity (pattern recognition receptors)

Question 2

What are 2 major types of protective reactions of the innate immune system?

Answer 2

Inflammation, antiviral defences

Question 3

What (3) is the immune system made of?

Answer 3

1. Physical and chemical barrier (skin, mucus membranes
2. Immune cells (neutrophils, monocytes)
3. Soluable factors, blood proteins (cytokines and complement)

Question 4

What are RLRs, and what do they recognise?

Answer 4

RIG- like receptors, Vidal RNA

Question 5

What are CDSs, and what do they recognise?

Answer 5

Cystolic DNA Sensors, microbial DNA

Question 6

What are NLRs, and what do they recognise?

Answer 6

NOD-like receptors, bacterial cell wall components