1
Q
What causes albinism?
A
Defect in melanin production
2
Q
What is a common mutation/problem in patients with Xeroderma Pigmentosum?
A
Nucleotide excision repair
3
Q
What areXP patients at risk for?
A
Very high risk: Basal cell and squamous cell carcinoma
High risk: melanoma
4
Q
What other cancers are XP patients at risk for?
A
Oropharyngeal squamous cell carcinoma Ocular CNS Colorectal Lung Bladder Prostate Ovarian
5
Q
What are carcinogens for XP patients to avoid?
A
Tobacco Alcohol HPV Processed meet Occupational (dyes, etc)
6
Q
Secondary symptoms of XP?
A
Corneal clouding and ulceration
Neurological degeneration
7
Q
Most XP patients live beyond age ___.
A
20
8
Q
What is anticipation?
A
Earlier onset
9
Q
Does Dyskeratosis congenita (DK) show anticipation?
A
Yes
Molecules to Cells
flashcards
Decks in class (34)
# Cards
-
Protein Structure and Function62
-
Protein Folding and Misfolding30
-
Protein Misfolding and Disease23
-
Enzymes pt. 153
-
Stem Cells7
-
Enzymes pt. 2 and 378
-
Enzymes in Pharmacology2
-
DNA Structure and Function46
-
Genetics Foundations18
-
DNA Replication39
-
Chromosomes and Chromosomal Abnormalities37
-
Cell Cycle19
-
Apoptosis18
-
Mitochondrial genetics9
-
DNA Replication in Eukaryotes47
-
RNA31
-
RNA Processing and Gene Splicing18
-
tRNA14
-
Protein synthesis pt. 230
-
RNA Processing27
-
Protein Synthesis23
-
Control of Gene Expression29
-
Cell Signaling28
-
Imprinting11
-
Control of Translation17
-
Protein Synthesis pt. 320
-
Molecular Techniques in Medicine17
-
Protein folding and misfolding (Ross)20
-
Enzymes (Ross)22
-
Integrated Clinical Correlation9
-
Practice questions32
-
Cancer genetics21
-
DNA modification and repair16
-
Clinical cases/drugs21
