NAPLEX Prep > Intro Info > Flashcards

Intro Info Flashcards

(8 cards)

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1
Q

what drugs are the big CYP inducers?

A

PS PORCS

  • Phenytoin
  • Smoking
  • Phenobarbital
  • Oxcarbazepine
  • Rifampin
  • Carbamazepine
  • St. John’s Wort
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2
Q

what drugs are the big CYP inhibitors?

A

G PACMAN

  • grapefruit
  • Protease inhibitors (PIs)
  • Azole antifungals
  • C (cyclosporine, cimetidine, cobicistat)
  • Macrolides
  • Amiodarone
  • Non-DHP CCBs
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3
Q

Common prodrugs ?

A
  • Clopidogrel
  • codeine
  • Primidone
  • capecitabine
  • valacyclovir
  • enalapril
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4
Q

what is the active metabolite for codeine?

A

morphine

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5
Q

what is the active metabolite for primidone?

A

phenobarbitol

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6
Q

what is the active metabolite for capecitabine?

A

fluorouracil

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7
Q

what is the active metabolite for enalapril?

A

enalprilat

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8
Q

what is the active metabolite for valacylovir

A

acyclovir

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