Intro Lecture

Question 1

colonisation

Answer 1

microbe present in human body without inflammatory response

Question 2

Sepsis =

Answer 2

dysregulated host response to infection

Question 3

septicaemia =

Answer 3

non-specific, doesn’t really mean anything

Question 4

septic shock =

Answer 4

subset of sepsis, circulatory and cellular/metabolic dysfunction associated with a higher risk of mortality

Question 5

SIRS =

Answer 5

Systemic Inflammatory Response Syndrome

Question 6

SIRS criteria

Answer 6

2 or more of the following:

• temp >38 or <36
• HR >90bpm
• RR >20
• WBC count >12k or <4k (10% immature neutrophils)

Question 7

Sepsis (SIRS) =

Answer 7

SIRS with a presumed or confirmed infectious process

Question 8

Septic shock (SIRS) =

Answer 8

Sepsis + at least one acute organ dysfunction

Question 9

septic shock mortality =

Answer 9

25-50%

Question 10

SOFA =

Answer 10

Sequential (sepsis related) Organ Function Assessment [useful in ICU BUT not useful in emergencies - so shorter version made.

Question 11

qSOFA =

Answer 11

SOFA but QUICK!

Question 12

qSOFA parameters =

Answer 12

• RR >22
• sBP <100mmHg
• Altered GCS (<14)

Question 13

the role of NEWS =

Answer 13

• Score of 5 or greater

- Patient suspected to have infection