1
Q
What is the definition of sterile?
A
Free from all living forms of life
2
Q
Sterilisation is a “________” phenomenon
A
All-or-nothing
3
Q
What sort of chemical reaction is sterilisation?
A
First-order
Population decreases exponentially (never reaches zero!)
4
Q
What does SAL stand for?
A
Sterility Assurance Level
5
Q
What does PNSU stand for?
A
Probability of a Non-Sterile Unit
6
Q
What is the definition of Bioburden?
A
Amount of bacteria in the produce BEFORE sterilisation
7
Q
What is the minimum standard for PNSU/SAL of pharmaceutical products
A
10^-6
Applied Pharmaceutical Microbiology
flashcards
Decks in class (15)
# Cards
-
Introduction7
-
Microbial Contamination22
-
Sterilisation processes and survival of bacteria12
-
Moist heat sterilisation20
-
Other sterilisation processes26
-
Control of sterilisation processes13
-
Sources of contamination22
-
Sensitivity of micro-organisms to inactivation11
-
Disinfectants, Antiseptics and Preservatives27
-
Classes of agent14
-
Mode of action and mechanisms of resistance15
-
Pharmaceutical microbiology28
-
Definitions/Calculations16
-
Survival curves4
-
Interview behaviour questions10
