Dose is…
the amount of drug taken at any one time
Efficacy is…
the ability of the drug to cause physiologic response when it interacts with a receptor
Potency (Affinity) is…
the amount of drug necessary to produce an effect of a given magnitude
Therapeutic index
TI = TD50 / ED50
the ratio of the dose that produces toxicity to the dose that produces a clinically desired response
Therapeutic window
Measures drug’s safety
Larger values indicates a wide range margin between doses that are effective and doses that are toxic