Iron Overload

Question 1

What is the techinical name for this?

Answer 1

Hyperferritinaemia

Question 2

It has a range of causes.

What genetic disease can cause this?

What iatrogenic cause is there?

Answer 2

Haemochromatosis

Chronic blood transfusion

Question 3

Complications:

What MSK issues does it cause?

What endocrine organs does it create deposits in, therefore damaging?

What may the skin look like?

Patients with hyperferritinaemia not due to haemochromatosis do not get these

Answer 3

Joint damage
Osteoporosis

Pancreas - DM
Gonads
Thyroid

Bronzed skin

Question 4

What is the main Rx?

What should be avoided in their diet?

Answer 4

Venesection and top up with saline

Iron and Vit C
Reduce alcohol