Define conttaception
The intentional prevention of contraception through use of various devices
What are the modes of action of copper IUDS
The copper IUD is a foreign body that creates a sterile inflamm reaction that is toxic to the sperm and ova and impairs implantation
Other modes of action
Causes changes in cervical mucus that inhibit sperm transport
Is thought to be spermicidal
Inhibits implantation by causing chronic inflammatory changes and thinning of the endometrium
Is thought to be ovicidal
Women who cannot use IUCD(MEC3/4)
Women who are pregnant
Between 48hrs and 4 weeks after delivery
Puerperal sepsis/post septic abortion
Unexplained vaginal bleeding
GTD
Pelvic cancer
Fibroids distorting the endometrial cavity
Congenital uterine/cervical anomalies
Current PID/cervicitis
High individual likelihood of exposure to gonorrhea/Chlamydia
Timing of IUCD insertion
Interval insertion- during menstrual cycle and woman is not pregnant
Postpartum insertions- Immediately after SVD or CS, past 48 hours wait to 6 wks
Post abortion- immediately, no infection
Complications of IUCD insertion
Uterine perforation (rare 1:1000 insertions)
Increases risk of pelvic inflammatory disease in high risk patients
Missing strings
Expulsion
Pregnancy with IUCD
Cramp like pain
Methods of removal of IUCDs
(i) Specially designed blunt hook
(ii) Artery forceps (Fig. 42.8)
(iii) Uterine curette (Fig. 42.17)
(iv) Hysteroscopically under direct vision
The indications of its removal are
missing threads, persistent pelvic pain, menorrhagia, pregnancy, displacement of the device and flaring up of pelvic infection.
Mode of action of hormone releasing IUS
They are also called intra-uterine systems (IUS)
They release levornogestrel, a progesterone hormone,
Types of hormone releasing IUS
Mirena®: contains 52mg of levornogestrel - 8years
Kyleena 19.5 mg - 5years
Skyla: contains 13.5 mg of levornogestrel - 3 years
Moa of hormonal IUS
Release a progestin, levonorgestrel.
Levonorgestrel:
suppresses ovulation
thickens cervical mucus, prevents sperm penetration
makes the endometrium thin, hence unsuitable for implantation
Who cannot use medicated iucd
Acute DVT/Pulmonary Embolus
Severe liver cirrhosis/Hepatocellular carcinoma
Breast cancer
SLE
Migraine headaches with aura
Breastfeeding women before 4 weeks postpartum
How are intrauterine devices broadly classified based on their design?
They are classified as “open” devices (e.g., Lippes loop, Cu T, Multiload) and “closed” devices (e.g., Grafenberg ring). Closed devices are now obsolete because they pose a risk of strangulating the gut if they accidentally perforate into the peritoneal cavity.
What are the main types of medicated IUCDs currently in use?
The currently used medicated IUCDs include Multiload 250, Multiload 375, Cu T 380A, Levonorgestrel intrauterine system (LNG-IUS), and GyneFix.
What is the effective lifespan before replacement is required for the Cu T 380A device?
The Cu T 380A device is replaced every 10 years.
How much hormone does the LNG-IUS contain, and at what rate is it released?
The LNG-IUS acts as a steroid reservoir containing 52 mg of levonorgestrel, which is released at a rate of 20 µg/day.
What is the primary mode of action of IUCDs in preventing pregnancy?
They produce a nonspecific inflammatory reaction and biochemical changes within the endometrium that possess gametotoxic and spermicidal properties.
How does the addition of copper enhance the contraceptive effect of an IUCD?
Ionized copper has a local antifertility effect that prevents blastocyst implantation through enzymatic interference. Copper also initiates the release of cytotoxic cytokines.
What is the specific mechanism of action for the Levonorgestrel Intrauterine System (LNG-IUS)?
It induces strong and uniform suppression of the endometrium and causes the cervical mucus to become very scanty.
What are the absolute contraindications for inserting an IUCD?
Contraindications include the presence of pelvic infection (current or within 3 months), undiagnosed genital tract bleeding, suspected pregnancy, distortion of the uterine cavity’s shape, and a past history of ectopic pregnancy.
What are the specific additional contraindications for inserting a copper-bearing IUCD?
Wilson’s disease and copper allergy are specific contraindications for copper IUCDs.
When are the generally accepted times to introduce an IUCD?
The device can be introduced in the interval period, following an abortion, or following childbirth.
Which specific insertion techniques are preferred for a Copper T device to prevent contamination and uterine injury?
The “withdrawal” technique and the “no-touch” insertion method are preferred.