Lynch Syndrome defect.
DNA mismatch repair.
reddish urine
rifampin
persistent diarrhea SE
macrolides (i.e. erythromycin)
renal failure and ototoxicity SE
vestibular disturbance SE
aminoglycoside
severe skin rashes on sunlight exposed skin SE
tetracclines
Two major syndromes that deal with loss of imprinting/inactivation bymethylation
Prader-Willi Syndrome (Paternal gene) Angelman Syndrome (Maternal gene)
plasma osm equation
P(osm) = 2[Na] + glucose/18 + urea/2.8
normal is 300
Total resistance of parallel
1/Rt = (1/R1) + (1/R2) + (1/R3)
total resistance in series
Rt = R1 + R2 + R3
Mean arterial pressure equation
MAP = CO x TPR
MAP = (HR x SV) x TPR