What is the benefit of using LMWH compared to unfractionated heparin in a pregnant pt w/ DVT?
longer half life
more predictable dose-response relationship
less likely to cause thrombocytopenia and hem. complications* (most important)
(NEITHER cross placenta or cause teratogenesis)
Warfarin embryopathy sx?
nasal hypoplasia
stippled vertebral/femoral epiphyses
2nd and 3rd T exposure to warfarin can cause what sxs?
hydrocephaly, microcephaly, ophtho abnormalities, IUGR, developmental delay
What are the complications of overt hypothyroidism in pregnancy?
inc risk of pre-eclampsia, LBW, preterm labor, placental abruption, MR
dx of primary amenhorrhea?
absence of menses at age 14 without secondary sex characteristics; or at 16 w/ secondary sex char.
another name for Mullerian agenesis?
Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome
What is absent w/ Mullerian agenesis?
What is present w/ Mullerian agenesis?
normal external genitalia/sex characteristics (tanner stage IV: breasts/pubic hair because ovaries do NOT originate from Mullerian duct)
- lower vagina (comes from urogenital sinus) ends in blind pouch
primary amenorrhea w/ bulging membranes b/w labia and hematocolpos. dx?
imperforate hymen. usually requires sx
inability to produce GnRH?
Kallman syndrome
(neurons fail to migrate) -> anosmia; no breast development. DO have uterus
Criteria for discharge of a post-op pt?
Indications for neurosurgery for prolactinoma?
Contraindications for tolterodine use for urge incontinence?
- CI in urinary retention, gastric retention, narrow angle glaucoma or allergy
Contrast PID with TOA
both have ascending infxn from upper gential tract
TOA tx
IV clindamycin and gentamycin
other indications for inpt IV clinda/gent
indications for inpatient:
DOC for acute PID without TOA?
oral ofloxacin for 14 days
what is pseudocyesis and how do you dx it?
woman convinced she is pregnant when she is not
When to give Rhogam?
How to determine Rhogam dose w/ fetomaternal hemorrhage?
What should be given before an epidural is placed?
antacid to increase the stomach pH (help prevent aspiration pneumonitis should aspiration occur w. general anesthesia)
persistent scaling, eczematous, ulcerated lesion of nipple/areolar complex. dx?
paget disease of the breast;
often coexists w/ DCIS
what is expected microscopically w/ pagets of breast?
individual adenocarcinoma cells of the epidermis
Causes of face presentation (instead of normal occiput pres)
can continue w/ normal vaginal delivery