1
Q
What is the one ketolide we need to know and what does it target?
A
It is Telithromycin and it increases G+ activity
2
Q
Where does telithromycin concentrate?
A
In pulmonary tissues and WBCs
3
Q
What will telithromycin be used for?
A
Acquired respiratory infections
4
Q
What is telithromycin active against?
A
Beta-lactam and macrolide resistant microbes
5
Q
How does telithromycin act?
A
Inhibits CYP2A4, prolongs Q-T
6
Q
What is a possible dangerous side effect of telithromycin?
A
It’s rarely hepatotoxic
7
Q
What is the black box warning for telithromycin?
A
Contraindicated in myasthenia gravis. May cause fatal or life-threatening respiratory failure
IDIT Final Pharm
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