(L28- Using Antimalarials)

Question 1

Indicate drug for:

• Uncomplicated Malaria
• P. falciform
• no known resistance

Answer 1

chloroquine (hydroxychloroquine)

Question 2

Indicate drug for:

• Uncomplicated Malaria
• P. falciform
• chloroquine-resistance (or choices for unknown resistance)

Answer 2

1) Malarone = atovaquone + proguanil
2) Coartem = artemether-lumefantrine
3) quinine + doxycycline
4) mefloquine

Question 3

Indicate drug for:

• Uncomplicated Malaria
• P. malariae
• all regions (= no known resistance)

Answer 3

chloroquine (hydroxychloroquine)

Question 4

Indicate drug for:

• Uncomplicated Malaria
• P. vivax, P. ovale
• all regions (= little known resistance)

Answer 4

chloroquine (/hydroxychloroquine) + primaquine

Question 5

Indicate drug for:

• Uncomplicated Malaria
• P. vivax
• chloroquine-resistant

Answer 5

1) quinine + doxycycline + primaquine
2) Malarone (= atovaquone-proguanil) + primaquine
3) mefloquine + primaquine

Question 6

Indicate drug for:

• Uncomplicated Malaria in Pregnancy
• all species of Plasmodium
• no known resistance

Answer 6

chloroquine (hydroxychloroquine)

Question 7

Indicate drug for:

• Uncomplicated Malaria in Pregnancy
• P. falciparum
• chloroquine-resistant

Answer 7

1) mefloquine

2) quinine + clindamycin

Question 8

Indicate drug for:

• Uncomplicated Malaria in Pregnancy
• P. vivax
• chloroquine-resistant

Answer 8

mefloquine

Question 9

Indicate drug for:

• Uncomplicated Malaria in Pregnancy
• P. vivax, P. ovale
• prophylaxis

Answer 9

chloroquine

Question 10

Indicate drug for:

• Severe Malaria
• all species, all regions
• route of administration

Answer 10

1) quinidine + doxycycline/clindamycin (IV) —- with progression to quinine + doxycycline (oral)

2)
1st- artesunate
2nd- Malarone (atovaquone-proguanil) OR clindamycin OR mefloquine

Question 11

Indicate drug for:

• Severe Malaria in Pregnancy
• all species of Plasmodium, all regions
• 1st trimester

Answer 11

1) quinidine

2) artesunate

Question 12

Indicate drug for:

• Severe Malaria in Pregnancy
• all species of Plasmodium, all regions
• 2nd/3rd trimester

Answer 12

1) artesunate

2) artemether

Question 13

Indicate drug for:

• Malaria chemoprophylaxis
• all species of Plasmodium, all regions
• not a known region with resistance

Answer 13

chloroquine

Question 14

Indicate drug for:

• Malaria chemoprophylaxis
• all species of Plasmodium, all regions
• known region with chloroquine-resistance

Answer 14

1) mefloquine
2) doxycycline
3) primaquine

Question 15

Indicate drug for:

• Malaria chemoprophylaxis in Pregnancy
• all species of Plasmodium, all regions
• not a known region with resistance

Answer 15

chloroquine

Question 16

Indicate drug for:

• Malaria chemoprophylaxis in Pregnancy
• all species of Plasmodium, all regions
• known region with chloroquine-resistance

Answer 16

mefloquine