L33 Flashcards

(29 cards)

1
Q

Primary indication for antidepressants?

A

Major depressive disorder

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2
Q

Neurotransmitters affected?

A

Serotonin and norepinephrine

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3
Q

Onset of action of Selective Serotonin Reuptake Inhibitors?

A

Two to three weeks

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4
Q

Most common side effect of Selective Serotonin Reuptake Inhibitors?

A

Sexual dysfunction

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5
Q

Best time of administration of Selective Serotonin Reuptake Inhibitors?

A

Morning

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6
Q

Onset of action of Tricyclic Antidepressants?

A

Four to six weeks

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7
Q

Major side effects of Tricyclic Antidepressants

A

Anticholinergic effects and sedation

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8
Q

Best dosing time of Tricyclic Antidepressants?

A

Bedtime

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9
Q

Most Dangerous complication of monoamine oxidase inhibitors?

A

Hypertensive crisis

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10
Q

Cause of hypertensive crisis?

A

Ingestion of tyramine-containing foods

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11
Q

Example of tyramine-rich food?

A

Aged cheese

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12
Q

Dangerous drug interaction?

A

Selective serotonin reuptake inhibitors

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13
Q

Gold standard treatment for bipolar disorder?

A

Lithium

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14
Q

Therapeutic serum level?

A

Zero point six to one point two milliequivalents per liter

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15
Q

Early sign of lithium toxicity?

A

Diarrhea

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16
Q

Severe toxicity outcome?

A

Coma or death

17
Q

Drug that increases gamma-aminobutyric acid?

A

Valproic acid

18
Q

Serious effect of carbamazepine?

A

Agranulocytosis

19
Q

Life-threatening reaction of lamotrigine?

A

Stevens–Johnson syndrome

20
Q

Neurotransmitter enhanced by benzodiazepines?

A

Gamma-aminobutyric acid

21
Q

Major risk of benzodiazepines?

A

Physical dependence

22
Q

Alcohol use with benzodiazepines causes what?

A

Severe central nervous system depression

23
Q

How should benzodiazepines be discontinued?

A

Gradual tapering

24
Q

Risk of dependence?

25
Onset of therapeutic effect?
Delayed
26
Primary indication for stimulant medications?
Attention deficit hyperactivity disorder
27
Paradoxical effect in children?
Calming effect
28
Common long-term effect in children?
Growth suppression
29
Serious adverse effect of pemoline?
Liver failure