emigration
movement of leukocytes out of blood vessels to get to sites of injury
5 types of leukocytes
eosinophils
basophils
neutrophils
lymphocytes
monocytes
eosinophils description
description
- stain red
- nucleus bilobed (nunchucks)
- 2x larger than RBC
eosinophils function
combats effects of histamine in allergic reactions, destroy parasitic worms
basophils description
basophils function
liberate histamine in allergic reactions that intensify inflammatory response
neutrophils description
neutrophils function
phagocytize, destry bacteria
lymphocytes description
lymphocyte function
monocytes description
monocytes function
phagocytosis (after transforming into fixed or wandering macrophages)
erythrocytes description
RBC
biconcave discs
no nucleus
erythrocytes function
transport O2 via hemoglobin
platelets descriptio
anucleate cell fragments
platelets function
form platelet plug, release chemicals that promote vascular spasm
sickle cell anemia (D and C)
sickle shaped RBCs
caused by substitution of an amino acid in hemoglobin protein of RBCs
can cause clumping of blood and breakdown of RBCs
Chronic lymphocytic leukemia
when lymphocytes divide. without constraint
looks like an ungodly amount of white blood cells
can be genetic
african sleeping sickeness
an infected fly carries trypanosome in saliva which produces necrotic damage to all contacted cells
look for worm things in blood
erythroblastosis fetalis
AKA hemolytic disease of the newborn
caused when an RH- mother has a second RH+ child. newborn will have a deficiency of RBCs due to mothers antibodies entering the fetal bloodstream
look for RBCs with nucleus
hematocrit
measure of the percent of RBCs in a sample
two conditions that can result in an increased hematocrit
dehydration
lung or heart disease
two conditions that can result in a decreased hematocrit
hemolysis
vitamin/mineral deficiency
source of antibodies in the antibody-mediated immune response
B cells