Na+
135-145
primary extracellular cation
Hyponatremia
- CHF
- Renal failure
-Liver disease
- SIADH
- Central Pontine Myelinolysis
K+
3.5-5.0
Primary intracellular cation
Chloride (Cl-)
96-106
Extracellular anion
Maintains osmotic pressure
Shifts with Na+
CO2
22-26
Same as HCO3 on ABG
Blood Urea Nitrogen (BUN)
8-23
Provides a picture of renal clearance
product of protein catabolism
Creatinine
0.7 - 1.4
Helps provide picture of renal clearance
produced at a steady rate
Glucose (Glu)
70-110
Ca++ Calcium
9-11
47% free
43% bound
10% chelated
RBC
5 million
Erythrocytes
Hemoglobin (Hgb)
15 g/DL
O2 binding
Hematocrit (Hct)
45%
percentage of blood that is formed elements within plasma
White blood cells (WBC)
4500 - 11,000
High
-sepsis
Low
-inflammation, infection, steroids,
Platelets (Plt)
150K - 400K
For clotting
Total Protein
6.0 - 8.0
consisist primarily of albumin and immunoglobulins
Albumin
3.5 - 5.5
Produced by liver
transport protein
70% of oncotic pressure
Coagulation panel
PT (Prothrombin Time)
PTT ( Partial Thromboplastin Time)
INR ( International Normalized Ratio)
PT (Prothrombin Time)
10 - 13 Seconds
extrinsic pathway
PTT (Partial Thromboplastin Time)
25-40 Seconds
Intrinsic Pathway
INR (International Normalized Ratio)
Normal INR: 1.0 seconds
Therapeutic INR: 2-3 seconds (anticoagulated)
Intrinsic Pathway
Triggered by endothelial damage inside of the vessel
Heparin works here
Monitored with PTT
Used in cardiac Pts like STEMI, DVT, PE
Clot dissolves in 7-10 days
Extrinsic Pathway
Triggered by tissue damage outside of the vessel (Trauma)
Releases tissue factor (Thromboplastin)
Depends on Vit. K
Monitored with PT and INR
Warfarin/Coumadin
If INR is high they bleed easily
Liver Function Test
ALT
AST
ALP
Albumin
Bilirubin
ALT (Alanine Transaminase)
7-55
Enzyme found in liver
Helps metabolize protein
AST (Aspartate Transaminase)
8-48
Enzyme that helps metabolize alanine, an amino acid.
Increase indicates liver or muscle damage