Abortion (miscarriage)
Decrease hCG
Anembryonic Pregnancy
Decrease hCG
Anecephaly
Increase MSAFP
Cephalocele
Increase MSAFP
Down Syndrome (Trisomy 21)
Increase hCG
Decrease Estriol
Decrease MSAFP
Ectopic Pregnancy
Decrease hCG
Edwards Syndrome (Trisomy 18)
Decrease Estriol
Decrease hCG
Decrease MSAFP
Gastroschisis
Increase MSAFP
Molar Pregnancy
(Markedly) Increase hCG
Omphalocele
Increase MSAFP
Patau Syndrome (Trisomy 13)
(Midly) Increase MSAFP
Spina Bifida (Meningocele or Myelomengiocele)
Increase MSAFP
Triploidy
Increase hCG (with molar)
Turner Syndrome
Decrease Estriol
Decrease hCG (with hydrops)
Decrease MSAFP