Laxatives

Question 1

6 classes

Answer 1

1. Irritants and stimulants
2. Bulk laxative
3. Saline and osmotic laxative
4. Stool softners
5. Lubricants
6. Cl channel activator

Question 2

Irritants and stimulants

Answer 2

Senna
biacodyl
castor oil

Question 3

Senna

Answer 3

1. contains sinnosides (anthraquinone glycoside)
2. evacuates bowel in 8-10hrs
3. treats opiod induced constipation with docusate

Question 4

Bisacodyl

Answer 4

1. stimulant of colon
2. not taken with antacids/ppi to prevtn premature dissolving of enteric coat
3. causes cramps and ATONIC COLON

Question 5

Castor oil

Answer 5

1. converted to ricinoleic acid which causes irration of gut

2. contraindicated in pregancy

Question 6

Bulk laxatives

Answer 6

methylcullulose
psyllium seeds
bran

Question 7

Bulk laxatives MOA

Answer 7

Hydrophillic colloids that form gels in intestine which causes water retentuon and distenstion to increase perilstalsis

Question 8

bulk laxatives are contraindicated in

Answer 8

bed ridden pts

Question 9

Saline and osmotic laxatives

Answer 9

Saline cathrartics (salts of magnesium and sodium)
Polyethlene glycol solutuons
lactulose

Question 10

MOA of saline cathartics

Answer 10

non absorb able salts that hold water in intestine that distends bwoel for defecation

Question 11

Used for radiological exam prep

Answer 11

polyethylene glycol solution

Question 12

causes least cramply

Answer 12

Polyethlyene gycol solution

Question 13

Lactulose

Answer 13

osmoatic laxative

Question 14

Stool softners

Answer 14

Docusate ssodium, calcium and potassium

Question 15

Lubricants

Answer 15

Mineral oil and glycerin suppositeries

taken orally upright

Question 16

CL channel activator

Answer 16

Lubiproston

used for chronic constipation