What is a Learning Disability (LD) or Intellectual Disability (ID)?
A group of conditions originating during the developmental period characterized by significantly below average intellectual functioning and adaptive behaviour, ≥2 SD below the mean (IQ < 70).
Which terms are used interchangeably with “Learning Disability” in the UK?
ID, intellectual disabilities, learning disability, learning difficulty, developmental delay (for young children).
How does ICD terminology differ?
ICD-10: Mental Retardation; ICD-11: Disorders of Intellectual Development (DIDe).
What are the 3 domains of adaptive functioning?
Conceptual skills, social skills, practical skills.
What is the mean IQ and diagnostic cutoff for ID?
Mean IQ = 100; <70 = intellectual disability.
What proportion of ID cases have an unknown cause?
About 60%.
Name the main categories of biological causes.
Genetic and non-genetic factors.
Give examples of genetic causes of ID.
Chromosomal: Down’s syndrome
Single-gene: Fragile X (FRAX), Phenylketonuria, Rett’s, Duchenne Muscular Dystrophy
Copy number variants: Cri du chat, Angelman’s, Prader-Willi.
What are key antenatal risk factors for ID?
Alcohol, drugs, radiation, infections (TORCH), maternal diabetes, malnutrition, hypoxia.
Perinatal causes?
Birth asphyxia, prematurity, low birth weight, pre-eclampsia, birth trauma.
Postnatal causes?
Encephalitis, brain injury, toxins (lead), malnutrition, neglect, social deprivation.
What is the estimated prevalence of ID?
1–3% overall; <1% in developed countries; up to 6% in parts of Eastern Europe.
What is the distribution by severity?
Mild 85%, Moderate 10%, Severe 4%, Profound 2%.
Is ID more common in males or females?
Males.
How much lower is life expectancy in PWID (people with intellectual disability)?
Around 20 years lower than the general population.
Why are health problems often under-recognised?
Poor symptom communication; changes in behaviour may be the only sign.
List 3 categories of health conditions in ID.
ID-related (e.g. epilepsy)
Syndrome-related (e.g. hypothyroidism in Down’s)
Secondary conditions (e.g. constipation, obesity).
Are mental disorders more common in people with ID?
Yes—much higher rates across all ages.
What are common coexisting conditions?
Neurodevelopmental disorders (ASD, ADHD, tics)
Acquired mental illnesses (depression, psychosis)
Challenging behaviours
Offending behaviour.
What are key signs of anxiety in ID?
Behavioural equivalents—agitation, crying, withdrawal, hyperactivity, physiological changes (sweating, vomiting).
Key features of depression in ID?
Sadness, anhedonia, fatigue ≥2 weeks. Behavioural signs: aggression, SIB, irritability, loss of self-care.
What are “behavioural equivalents” of mania in ID?
Excessive smiling, reduced sleep, pressured speech, sexualised or hyperactive behaviour.
Why is diagnosing psychosis harder in severe ID?
Communication deficits make it difficult to elicit delusions/hallucinations.
Define “challenging behaviour.”
Socially unacceptable behaviour causing distress/harm that requires intervention.