what is the purpose of kreb’s cycle?
produce:
- 6 NADH
- 2 ATP
- 2 FADH2
what is the purpose of glycolysis?
- turn 6C glucose into 2 x 3C pyruvates (via aldolase)
- produce 2 net ATP (2 used, 4 gained)
- produce 2 NADH2
how the FUCK does the ETC chain work
buckle in pussies we’re about to go turbo
- NADH –> 2e- + (H+) + NAD+
electrons are handed off to c1 - c1 doesn’t want e-, so it gives e- to Q
- at the same time, at c2, succinate donates e- to FAD+ to become FADH2
c2 doesn’t want e-, so it also gives e- to Q - Q donates 2 e- to c3
- c3 doesn’t want e- –> gives to cyt C
- cyt C donates e- to c4, which gives it to oxygen (forms water)
- hella H+ buildup in the intermembrane space. ATP synthase provides a channel for H+ to move down the gradient back into the matrix, at the same time producing ATP
is glycolysis aerobic? what about kreb’s cycle? ETC?
glycolysis and kreb’s do not require oxygen. ETC does.
what is the purpose of converting pyruvic acid to lactic acid if we have the ETC?
LDH pathway doesn’t require oxygen + can reliably regenerate NAD to repeatedly get energy
drawback is that lactic acid is produced as a byproduct and that’s not good for the body :(
what are phosphogens? what are they good for? how does the mice experiment exhibit this?
high energy storages similar to ATP where it has a Pi chilling ready for use
creatine phosphate + ADP <–> creatine + ATP
good for burst activity! (mice experiment where creatine gene was knocked out)
compare aerobic, anaerobic, and phosphagen use in terms of:
- stability
- energy yield
- recovery
stability: aerobic > anaerobic, phosphagen
energy yield: aerobic > anaerobic > phosphagen
recovery (to aerobic): phosphagen > anaerobic (anaerobic requires addressing all the lactic acid buildup)
