Lecture 1

Question 1

biphytanyl and phytanyl

Answer 1

archaeal membrane

pytanyl - repeating isoprene units

Question 2

fxns of the cytoplasmic membrane

Answer 2

1. permeability barrier
2. protein anchor
3. energy conservation

Question 3

facilitated diffusion vs. passive diffusion

Answer 3

facilitated diffusion increases the rate of diffusion compared to passive diffusion
facilitated diffusion proteins can operate in both directions, saturable process

Question 4

Group translocation

Answer 4

• mark the sugar with phosphate
• inducer exclusion: prevents uptake of other sugars/substrates (preferred carbon source)
• phosphotransferase system

Question 5

Cell Wall

Answer 5

lysozyme - breaks B1-4 bond
transpeptidation occurs between the peptide side chains.
bactoprenol coats the precursor so the hydrophobic precursor can make it to the periplasm.

Question 6

Lantibiotics

Answer 6

• bacteriocins (cationic, amphiphilic)
• bacterial warfare
• inhibit cell wall synthesis by scavenging and binding to precursor lipid II
• can also form pores