Lecture 2 - Phosphorous

Question 1

Phosphorus normal range

Answer 1

2.5 - 4.5 mg/dL

Question 2

phosphorous

• critical element for cellular structure and function, respiratory/cardiac muscle function
• ___ reactions that control carbohydrate, fat, and protein metabolism
• source of high energy bonds of ___
• modulates the oxygen carrying capacity of ___ as 2,3-diphosphoglycerate
• regulated by intake, vitamin D, parathyroid hormone, and renal function

Prof’s favorite bc it is resposible for so many jobs

Answer 2

• enzymatics
• ATP
• hemoglobin

Question 3

Hypophosphatemia

Mild to moderate
- PO4 concentration ___ mg/dL

Severe
- PO4 < ___ mg/dL
- goal in ICU may be higher ( > or equal to 3 mg/dL)

Etiologies
- decrease intake
- impaired absorption
- intracellular shifts

Answer 3

• 1-2
• 1

Question 4

hypophosphatemia treatment

mild to moderate
- Oral PO4
- ___ (10 mMol Phos/packet) = 30-60 mMol/day in 2-3 divided doses

Severe
- ___ PO4
- available as K or Na salts
- use KPhos when K < 4 mEq/L
- use NaPhos when K > or equal to 4 mEq/L

Answer 4

• Phos-NaK
• IV

snack

Question 5

Hypophosphatemia example treatment guidelines

• PO4 concentration (2.3-2.9 mg/dL): ___ mMol/kg
• PO4 concentration (1.6-2.2 mg/dL): ___ mMol/kg
• PO4 concentration (< 1.6 mg/dL): ___ mMol/kg

Answer 5

• 0.32
• 0.64
• 1

Question 6

Phos Replacement

• 1 mMol NaPhos = ___ mEq Na + ____ mEq Phos
• 1 mMol KPhos = ___ mEq K + ___ mEq Phos

Administration
- give PO divided doses
- infused IV doses no faster than ___ mMol/hr
- remember potassium rules for infusion also

Answer 6

• 1.33, 1.33
• 1.47, 1.47
• 7

Question 7

Hyperphosphatemia

etiologies
- ___ failure/insufficiency
- hypoparathyroidism
- excessive exogenous intake

Answer 7

renal

Question 8

clinical presention of hyperphosphatemia

soft tissue calcification
- when Ca x PO4 product is > ___
- concurrent ___

Answer 8

60
hypocalcemia

Question 9

treatment hyperphosphatemia

Severe symptomatic hyperphosphatemia
- IV ___

Decrease phosphate ___ absorptions

Answer 9

calcium
GI