Lecture 4 - Bioinformatics

Question 1

In the Blosum-62, what is indicated by a - number when substituting amino acids?

Answer 1

Dissimilar substitution (different chemistries)

Question 2

Substitution introduces AA that is similar in size/chemical properties as the substituted AA

Answer 2

Conservative

Question 3

Substitution introduces AA that is not similar in size/chemical properties as the substituted AA

Answer 3

Non-conservative

Question 4

How many points are awarded for a similar amino acid in the sliding analysis of AAs?

Answer 4

+10

Question 5

How many points are added to gaps in sliding analysis of AAs?

Answer 5

-10

Question 6

In the Blosum-62, what is indicated by a + number when substituting amino acids?

Answer 6

Similar amino acids (regarding chemistry)