Lecture 5

Question 1

How is gene expression controlled?

Answer 1

At the DNA level
At the transcriptional level - cis sequences, promoter choice and trans factors
At the post-transcriptional level - maturation, alternative splicing, edition, mRNA stability
At the transport level
Regulatory processes of function of protein - ligands, covalent modification, partial proteolysis

Question 2

List the forms of slow regulation

Answer 2

Transcriptional regulation
Translational control
Quantity
Location
Lifetime

Question 3

List the forms of fast regulation

Answer 3

Regulatory ligands, Covalent modification, partial proteolysis