Lectures 1-3

Question 1

What is exudate?

Answer 1

Mass of cells and fluid seeping out from blood vessels or an organ. Typically during inflammation.

Question 2

What is the fluid in exudate made of?

Answer 2

• fibrin
• serum
• WBCs

Question 3

Name vasodilators in inflammation.

Answer 3

• prostaglandins

- histamine

Question 4

Name chemical mediators in inflammation that cause vascular permeability.

Answer 4

• vasoactive amines
• C3a and C5a
• Bradykinin
• leukotrienes C4, D4, E4, PAF

Question 5

What chemical mediators of inflammation cause chemotaxis?

Answer 5

• C5a
• leukotriene B4
• lipids
• bacterial products

Question 6

Chemical mediators of fever?

Answer 6

• IL-1
• TNF
• prostaglandin E2

Question 7

Chemical mediators of pain?

Answer 7

• prostaglandins

- bradykinin

Question 8

Chemical mediators of tissue injury?

Answer 8

• lysosomal enzymes (neutrophils, macrophages) - oxygen metabolites