Leptospirosis

Question 1

Weil syndrome

Answer 1

Hemorrhage
Jaundice
Acute kidney injury

Question 2

Rx severe leptospirosis

Answer 2

IV penicillin 1.5 q6
Ceftriaxone 2g/IV
Cefotaxime 1g q6

Question 3

Mild leptospirosis

Answer 3

Doxycycline 100 bid
Azithromycin 500 bid
Amoxicillin

Question 4

Definitive diagnosis of leptospirosis

Answer 4

Isolation of the organism or

PCR antibody 1:200-800 in MAT