Lesson 7 Flashcards

Neuroscience and biopsychology (82 cards)

1
Q

What are the four main parts of a neuron?

A

The four main parts of a neuron are the cell body, dendrites, axon, and axon terminal.

The cell body houses the genetic material; dendrites receive signals from other neurons; the axon carries signals away from the cell body; and the axon terminal sends signals to other neurons.

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2
Q

What is the role of the somatic nervous system?

A

The somatic nervous system includes sensory (afferent) neurons that bring information from the senses to the brain and motor (efferent) neurons that send information from the central nervous system to the muscles.

It is responsible for voluntary movements and sensory processing.

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3
Q

What is the function of the autonomic nervous system?

A

The autonomic nervous system controls activities outside of conscious control, such as digestion and respiration.

It is divided into the sympathetic system (energy-spending) and the parasympathetic system (energy-preserving).

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4
Q

What is the purpose of myelin in a myelinated neuron?

A

Myelin acts as insulation that speeds up neurotransmission.

It comes from glial cells like Schwann cells.

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5
Q

What are the nodes of Ranvier?

A

The nodes of Ranvier are gaps in the myelin sheath that help propagate the electrical signal down the axon.

They play a crucial role in the efficiency of action potential transmission.

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6
Q

Describe the process of an action potential.

A

An action potential begins with a resting potential of -70mv, depolarizes to a threshold (e.g., -55mv), fires an impulse down the axon, and enters a refractory period as it returns to resting potential.

This process involves electrochemical changes within the neuron.

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7
Q

What are neurotransmitters?

A

Neurotransmitters are chemical messengers that transmit signals from one neuron to another across a synapse.

They play critical roles in various brain functions.

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8
Q

What specific functions are associated with dopamine?

A

Dopamine facilitates movement, reward/pleasure, and concentration.

It is linked to conditions such as Parkinson’s disease, schizophrenia, and drug addiction.

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9
Q

Define neuroplasticity.

A

Neuroplasticity is the brain’s ability to reorganize and form new neural connections, allowing for adaptation, learning, and recovery from injury.

It can involve changes in the number or length of dendrites, neuron size, glial cell number, or synapse count.

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10
Q

List the four lobes of the cerebral cortex.

A

The four lobes are:
* Frontal lobe
* Temporal lobe
* Parietal lobe
* Occipital lobe

Each lobe has distinct primary functions.

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11
Q

What is the primary function of the frontal lobe?

A

The frontal lobe is responsible for higher cognitive functions.

This includes decision making, problem-solving, and planning.

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12
Q

What is Broca’s aphasia?

A

Broca’s aphasia is characterized by difficulty speaking fluently and forming grammatically correct sentences, though comprehension is relatively preserved.

It results from damage to the Broca’s area in the frontal lobe.

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13
Q

What is Wernicke’s aphasia?

A

Wernicke’s aphasia involves fluent but meaningless speech and impaired comprehension of spoken and written language.

It arises from damage to the Wernicke’s area in the temporal lobe.

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14
Q

Differentiate between cerebral infarction and anoxic brain injury.

A

A cerebral infarction is a loss of blood supply to part of the brain, while an anoxic brain injury occurs when the brain is deprived of oxygen for an extended period.

Both can lead to significant cognitive impairments.

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15
Q

What is anterograde amnesia?

A

Anterograde amnesia is characterized by difficulty forming new long-term memories after the onset of amnesia.

Task-based memory is often preserved.

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16
Q

What is retrograde amnesia?

A

Retrograde amnesia is characterized by difficulty remembering past events that occurred before the onset of amnesia.

General knowledge and skills are usually retained.

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17
Q

What is the resting potential of a neuron?

A

The resting potential of a neuron is typically -70mv.

This is the electrical potential when the neuron is not stimulated.

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18
Q

What role does GABA play in the central nervous system?

A

GABA is the major inhibitory neurotransmitter in the central nervous system, facilitating smooth movement and sleep.

huntingtons epilepsy anxiety

It helps regulate excitability in the nervous system.

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19
Q

What is the role of serotonin in mood regulation?

A

Serotonin is associated with better mood, less appetite, and better memory.

It plays a crucial role in conditions such as depression.

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20
Q

What is neurogenesis?

A

Neurogenesis is the formation of new neurons in the brain, which occurs throughout life.

It is essential for learning and recovery from injuries.

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21
Q

What are the functions of the temporal lobe?

A

The temporal lobe is responsible for auditory processing, language comprehension, and memory.

It plays a key role in processing sounds and understanding language.

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22
Q

What is hemineglect?

A

Hemineglect is a perceptual disturbance involving difficulty seeing, responding to, or acting on information from one side of the world.

It is often linked to damage in the parietal lobe.

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23
Q

What is the role of the corpus callosum?

A

The corpus callosum connects the two hemispheres of the brain.

It facilitates communication between the left and right sides of the brain.

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24
Q

What is the role of the thalamus?

A

The thalamus relays and processes sensory stimuli.

It acts as a hub for sensory information before it reaches the cerebral cortex.

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25
What is the medulla oblongata responsible for?
The medulla oblongata controls vital functions such as breathing and heart rate. ## Footnote It is located in the hindbrain.
26
What is prosopagnosia?
Prosopagnosia is characterized by the inability to recognize faces. ## Footnote It is a type of visual agnosia.
27
What are endorphins?
Endorphins are peptides that modify pleasure and pain signals in the brain. ## Footnote They are often referred to as 'feel-good' hormones.
28
What is the primary function of neurotransmitters within the nervous system?
Transmission of signals between neurons
29
What term describes the process by which the brain removes weak or unused synapses to strengthen neural connections and improve efficiency?
Synaptic pruning
30
With regard to the process of neural transmission, a refractory period occurs when:
positively charged atoms are pumped back outside a neural membrane
31
The process of forming new memories primarily involves which brain structure?
Hippocampus
32
Damage to which area of the brain is most likely to result in difficulties with language comprehension and production?
Wernicke's area
33
what is the role of glial cells in the NS?
supporting cell that help neurons to function: -provide structural support -supply nutrients and oxygen -insulation -destroy pathogens and remove dead neurons ## Footnote the pit crew in the brain if the racecar driver were the neurons
34
What are some examples of glial cells?
schwann cells, oligodendrocytes, astrocytes, ependymal cells, microglial cells
35
36
what do schwann cells do? | and what are they?
subtype of glial cells that provide myelin for sheaths on axons
37
38
what is contained within the neuron cell?
cytoplasm, nucleus, mitochondria, outer membrane
39
what is the function of mitochondria?
provide energy for the cell body to function via glucose
40
what does the axon hillock do?
acts as a "trigger zone" where incoming excitatory and inhibitory signals are summed to determine if an action potential (a nerve impulse) will be generated and sent down the axon. If the combined signals reach a threshold, the axon hillock initiates the all-or-none electrical signal, allowing the neuron to communicate with other cells.
41
what is acetylcholine?
a neurotransmitter that facilitates memory and movement. Plays a role in Alzheimers dementia (characterised by dysregulation of acetylcholine pathways in the brain)
42
what are high levels of norepinephrine associated with?
alertness, better mood, facilitates learning Autonomic functions - heart rate, BP Plays a role in depression
43
what is the major excitatory neurotransmitter in the CNS?
glutamate facilitates learning and memory
44
what health conditions are associated with dopamine?
parkinsons schizophrenia drug addiction
45
what does alcohol do to neurotransmitters?
Suppresses the actions of glutamate (excitatory transmitter) whilst increasing action of Gamma-amino butyric acid (GABA; inhibitory transmitter) resulting in the ‘depressant’ effect of alcohol (e.g., producing uncoordinated movement and drowsiness) * Also increases the actions of dopamine (i.e., reward/pleasure) resulting in decreased inhibitions (e.g., producing dumb actions/words when under the influence)
46
which 2 neurotransmitters does ecstacy/MDMA increase?
serotonin and dopamine
47
what conditions involve abnormal synaptic pruning?
too much - schizophrenia too little - autism and epilepsy
48
where does neurogenesis occur? ## Footnote what factors influence it? whcih cognitive functions is it linked to?
-hippocampus and olfactory bulb -influenced by exercise, environment, learning -linked to mood regulation, recovery from brain injuries
49
what cells are responsible for identifying adn removing unnecessary neural connections?
astrocytes and microglia
50
what does synaptic pruning do?
-refines neural circuits, optomising for more efficient brain processing -occurs mostly in childhood and adolescence -proliferation of brain neurons in childhood allows for neural flexibility and aids in rapid learnging and adaptation processes ## Footnote an excess of synapses can lead to inefficiency in neural circuits
51
what marker is associated with long term memory?
glutamate receptor NMDA activation major protective factor for a synapse
52
list the 9 parts of the forebrain
cerebral cortex suprachiasmatic striatum corpus callosum thalamus amygdala hippocampus septum
53
what are the 4 parts of the hindbrain?
locus coeruleus cerebellum reticular formation medulla oblongata
54
what are the 4 parts of the midbrain?
colliculi tegmentum substantia nigra cerebral peduncles
55
what is the role and function of the substantia nigra? ## Footnote where is is located?
* produces dopamine - regulates movement and rewards seeking behaviour * helps to coordinate smooth movement *located in the midbrain parkinsons
56
what kinds of processes is the cerebral cortex involved in? ## Footnote where is it located?
* problem solving * memory and attention * sensory perception * motor commands * language and reasoning * located in the forebrain
57
what is the role of the suprachiasmatic nuclei (SCN)? ## Footnote where is is located?
* maintains circadian rhythm * (pair) located in the hypothalmus (forebrain) above the optic chiasm *receives input from eyes for guiding light levels
58
where is the striatum located and what does it do?
* located in teh basal ganglia in the forebrain * coordinates smoothe movement * planning and execution of movement
59
what does the corpus callosum do? ## Footnote where is it located?
* connects hemispheres * supports language, comprehension, spatial orientation, memory consolidation * bundle of nerve fibres in the forebrain
60
what are the roles of the thalamus? ## Footnote where is it located?
* pair of egg shpaed structures, deep in the midbrain, above the brainstem * relays/processes sensory stimuli to the cerebral cortex * crucial role in regulating consciousness, attention and perception * processes and filters sensory stimuli before sending it to the appropriate ares of the cortex
61
what's the go with the hypothalamus? ## Footnote and where is it located?
* integrates various sensory, hormonal and neural signals to help use to survive and thrive. * helps to maintain homeostasis * basic physiological drives - hunger, thirst, sexual behaviour * forebrain
62
what does the amygdala do? ## Footnote where is it located?
* detects threats and forms emotional associations * controls emotional responses to emotions * fear and agression * located in the forebrain
63
what is the role of the hippocampus? ## Footnote where is it located?
* spacial navigation * helps to convert short term memory into long * episodic memory * emotional regulation * located in the forebrain
64
what is the role of the septum? ## Footnote where is it located?
* located in the forebrain * regulates emotions, motivation, and reward processing * pleasure and reinforcement reward circuits
65
what the heck is the locus coeruleus? ## Footnote and where is it located?
* located in the hindbrain * nucleus located in the brain stem * arousal, attention and stress response * approximately 1/2 brain volume of norepinephrine
66
what is the role of the cerebellum? ## Footnote where is it located?
* located in the hindbrain * coordinates and fine tunes motor activity * timing, precision of movement * language, attention and motor processing
67
what is the reticular formation and where is it located?
* arousal and attention * extends from the medulla oblongata in the hindbrain * regulates arousal and attention * consciousness and alertness * directs attention to relevant stimuli * inhibits response to irrelevant stimuli
68
what is the role of the medulla oblongata? ## Footnote where is it located?
* attached to the spinal cord in the hindbrain * controls vital survival functions - swallowing, vomiting, breathing, heart beat, bp * contains nuclei to regulate sleep
69
what are the roles of the 4 lobes of the cerebral cortex?
-frontal lobe: high cognitive functions -temporal lobe: auditory processing, language comprehension, memory -parietal: processes sonsory information and spatial awareness -occipital lobe: primarily visual processing
70
what is the role of colliculi? ## Footnote where is it's location?
* superior and inferior pairs * process visual and auditory signals * located in the midbrain
71
what is the tegmentum and where is it located?
* contains neurons for movement, coordination and pain suppression * located in the midbrain
72
what are cerebral peduncles? Where are they located?
* large nerve fibre bundles * connect brain stem to forebrain (signals) * located in the midbrain
73
what is the difference between an ischemic stroke and a haemorrhagic stroke?
Ischemic stroke: Blockage in an artery prevents blood flow to a part of the brain, leading to tissue damage due to lack of oxygen and nutrients * Hemorrhagic stroke: Results from a ruptured blood vessel in the brain, leading to bleeding and damage to surrounding tissu
74
how is hypoxic brain injury different to anoxic brain injury?
Similar to anoxic brain injury, but involves partial deprivation of oxygen rather than complete deprivation
75
what are the 3 main causes of brain damage?
* Infectious brain damage: Infections such as meningitis, encephalitis, and brain abscesses can cause inflammation, swelling, and tissue damage in the brain * Toxic brain damage: Exposure to certain toxins, such as lead, mercury, or carbon monoxide, can cause brain damage * Brain tumours: Both malignant and benign tumours can damage brain tissue by compressing surrounding structures or interfering with normal brain function
76
define a neurodegenerative disorder. what are 3 examples?
Involve progressive damage to nerve cells in the brain, leading to cognitive and motor impairments * Prominent examples: * Alzheimer’s disease * Parkinson’s disease * Huntington’s disease * Amyotrophic lateral sclerosis (ALS)
77
what are perceptual disturbances? what causes them?
Impairments in the ability to organise, recognise, interpret, and make sense of incoming sensory information * May result from damage to the whatpathway or the where pathway
78
what are two perceptual disturbances associated with the WHAT pathway?
* Visual agnosia: Inability to identify objects by their appearance. Still able to see, describe and draw the objects. * Prosopagnosia: Inability to recognisefaces (including own reflection). Damage to temporal lobe's facial recognition system.
79
what are two perceptual disturbances associated with the WHERE pathway?
Simultanagnosia: Ability to see parts of a visual scene but difficulty perceiving the whole scene. Damage or dysfunction to upper regions of the parietal lobes. * Hemineglect: Difficulty seeing, responding to or acting on information coming from one side of the world. May see both sides of the world, but are likely to pay attention to one side of the world and ignore the other. Damage or dysfunction to the parietal lobes.
80
what are two examples of meovement disorders?
Impairments in the ability to perform or coordinate previously normal motor skills. * Ideational apraxia: Individual movements needed to perform a task are all correctly executed, but in the wrong order. * Ideomotor apraxia: Difficulties in performing the skilled movements of a task
81
what is executive dysfuntion? what are some conditions associated with this? what kinds of management strategies used?
Refers to impairments in higher-order cognitive processes, such as: * Difficulties in planning, organisation, problem-solving, decision-making, working memory, inhibition, and goal-directed behavior * Impairments in executive function can result from various neurological conditions, brain injuries, or psychiatric disorders * Examples of associated conditions include: Traumatic brain injury, stroke, dementia, ADHD, ASD, and schizophrenia *Management strategies may involve: Cognitive rehabilitation, compensatory strategies, behavioral interventions, and medication when appropriate
82
why did phineas Gage survive his brain injury?
* damage was to the left frontal lobe (involved in decision making and emotional processing). * damage mostly to grey matter (approx 11%), rather then white matter (approx 4% loss). * White matter is easier to regenerate * area lost connections with orbitofrontal cortex of the frontal lobe to the limbic system.