leucocytes

Question 1

what percentage of WBC do neutrophils make up

Answer 1

70

Question 2

what is the primary job of neutrophils

Answer 2

phagocytose foreign molecules

Question 3

how do phagocytes/neutrophils work

Answer 3

• attracted to pro inflammatory molecules and antibody coated pathogens
• phagocyte engulds pathogens
• lysosome fuses with pathogen and breaks down material with lysozymes
• material is digested and antigens are presented on cell membrane
• antigen presenting cell is formed

Question 4

where does antigen presentation occur (most the time)

Answer 4

developing lymphocytes are often found in lymph nodes and other lymphoid tissues and its where antigen presentation often occurs

Question 5

recombination uses random gene alterations to constantly make new B cell / T cell receptors

Question 6

what virus typically attracts CD4 cells/t helper cells

Answer 6

HIV
human immunodeficiency virus

Question 7

what are 4 ways antibodies work

Answer 7

• direct neutralisation
• facilitating phagocytosis
• agglutination
• activating complement

Question 8

what is Hodgkins vs non-hodgkins

Answer 8

• non-Hodgkin lymphoma may arise in lymph nodes anywhere in the body
• whereas Hodgkin lymphoma typically begins in the upper body, such as the neck, chest or armpits.

Question 9

what can hodkins negatively affect the body

Answer 9

both can cause depression of all cell lines therefore bleeding, infection and anaemia

Question 10

what is multiple myeloma

Answer 10

plasma cell malignancy
- frequent invades bones and can lead to hypercalcemia, renal disease and anaemia