Leukons

Question 1

Hemogram

Answer 1

entire complete blood count

Question 2

Erythron

Answer 2

RBC counts, indices and morphologic assessment

Question 3

Leucon

Answer 3

WBC counts and morphology

Question 4

Thrombon

Answer 4

Platelet counts, indices, and morphology

Question 5

Another name for granulocytes

Answer 5

Polymorphonuclear cell (PMN)

Question 6

Types of Granulocytes

Answer 6

1. Neutrophil
2. Eosinophils
3. Basophils

Question 7

Another name for agranulocytes

Answer 7

Mononuclear cells

Question 8

Types of agranulocytes

Answer 8

1. Monocytes
2. Lymphocytes

Question 9

Methods of obtaining a leucon

Answer 9

1. PCV/TP
2. Machine analysis
3. Blood smear
4. CBC
5. Serum chemistry profile
6. Urinalysis

Question 10

Changes in morphology during granulocyte maturation

Answer 10

1. Decreases in cell size
2. Less basophilic (blue)
3. More indented, lobes
4. More coarse and condensed

Question 11

Different neutrophil pools

Answer 11

In Bone Marrow (3-5 days)
1. Proliferating Pool
2. Maturation Pool
3. Storage Pool
In Blood (8-10 hours)
4. Circulating Pool
5. Marginating Pool
In Tissues (1-2 days)
6. Tissue Pool

Question 12

What two pools are neutrophils able to easily move between?

Answer 12

Circulating pool and marginating pool

Question 13

Function of neutrophils

Answer 13

1.first responders to tissue injury or irritation
2. phagocytosis (phagolysosome)
3. bacterial killing (granules fuse with vacuoles)

Question 14

Eosinophils

Answer 14

1. granulocyte with pink granules and a segmented nucleus
2. takes 3-5 days to produce
3. in circulation for 30 mins
4. survives in tissues for 2 days

Question 15

Causes/Differentials for eosinophilia and basophilia

Answer 15

1. Parasites (GI, heartworm, flea allergies, P. tenuis)
2. Allergies/hypersensitivity (feline asthma, eosinophilic granuloma complex)
3. Neoplasia (lymphoma, mast cell tumors)
4. Fungal (cryptococcus, pithium

Question 16

Basophils

Answer 16

1. granulocyte with blue granules
2. has a narrow, long nucleus (ribbon)
3. produced in bone marrow

Question 17

Monocyte

Answer 17

1. a large agranulocyte with a blue cytoplasm
2. may contain colorless vacuoles
3. Contains a wide nucleus
4. Live in the blood for 1-1.5 days

Question 18

Why might vacuoles appear in neutrophils

Answer 18

It is actually foam

Question 19

Functions of a macrophage

Answer 19

1. Phagocytosis (damaged cells, bacteria, tumors)
2. Tissue healing
3. Immune response (antigen presentation, inflammation, fever)

Question 20

Lymphocytes

Answer 20

1. agranulocyte with a large nucleus
2. small cytoplasm
3. reacts to antigens
4. live for months to years
5. can leave blood and return