Montelukast (Singulair)
Tablets or granule packets
1-Adults
Zafirlukast (Accolate)
Tablets
5-Adults
Zileuton (Zyflo)
ER and IR tablets
Adults
Adverse effects
Neuropsychiatric events (agitation, anxiety, dreams, hallucinations, depression)
Churg Syndrome
Increased hepatic transaminases (Zafirlukast & Zileuton)
Counseling tips
Not used with COPD
Zafirlukast: at least 1-2 hr before meals, can increase INR
Zileuton: take with food