Anterior Cingulate Cortex (ACC)
Stores long term emotional memory
-operates through ANS through solitary tract and dorsal motor of X
Mid-Cingulate Cortex (MCC)
motivated behavior and response
anterior part
-action during fear
Amygdala
Sensory experience with emotional significance–> prominently FEAR!!
Hypothalamus
Autonomic/hormonal control
Periaqueductal gray (PAG)
Autonomic/skeletal behaviors
Locus Coeruleus (LC)
enhances storage of emotional memories
Uses NE
Dorsal Raphe Nucleus (DRN)
Regulates Mood
Primary emotion
Amygdala, hypothalamus, PAG
Secondary Emotion
Cortical limbic structures and hippocampus
LGN/MGN to amygdala
Straight pathway to evoke fear
LC–> uses NE to make sure you remember that fear
Ventromedial Hypothalamus (VMH)
rest and relaxing types of behaviors
Lateral Hypothalamus (LH)
defensive behaviors–> sham rage
Hypothalamic pituitary axis
control parasympathetics and sympathetic via the hypothalamus
Perigenual region
vulnerable to depression
Facial region of ACC
wear emotions on face
-impact facial region
Anterior MCC
fear
Ventral ACC
Sadness
Rostral ACC
Happiness
LC Coordination of motor outputs
Increased Amygdala volume
increase activity-> increase F-F
- high anxiety/depression
Decreased ACC volume
ACC puts breaks on amygdala
-major depression
Reduced glucose metabolism in ACC
Major depression
NE and 5HT
First treatment for mood disorders
SSRIs
Depression
-Dorsal raphe nuclei–produces 5HT to brain
helps Amgy, ACC and insula cortex of limbic system