Lipids

Question 1

phosphatidylcholine

Answer 1

glycerophospholipid

outer leaflet

Question 2

phosphatidyl serine

Answer 2

glycerophospholipid

exposed to surface of apoptotic cells - move from inner to outer

Question 3

cardiolipin

Answer 3

glycerophospholipid

abundant in INNER MITO MEMBR ONLY

Question 4

Dipalmitoylphosphatidylcholinde (DPPC)

Answer 4

-glycerophospholipid
-part of surfactant, low level in neonates so incr respiratory distress
L/S > 2 –> fetal lung mature
L/S < 1.5 –> not mature, incr risk RDS

Question 5

Plasmalogens and platelet activating factor (PAF)

Answer 5

• glycerophospholipid

- ether instead of ester linkage

Question 6

glycerophospholipid xture

Answer 6

glycerol backbone with 3 branches: 1 sat FA, 1 unsat FA, and base with phosphate

Question 7

sphingophosphylipid

Answer 7

is a type of phospholipid

-sphingomyelin

Question 8

sphingomyelin

Answer 8

• sphingophospholipid
• outer leaflet
• lipid raft
• abundant in MYELIN SHEATH
• sphingosine backbone with 2 branches: FA and choline w phosphate

Question 9

ceramine

Answer 9

sphingosine backbone with 1 FA

-used in sphingomyelin (sphingophospholipid) and all glycolipids

Question 10

glycolipids

Answer 10

• outer leaflet - form glycolax
• lipid raft
• impt in myelin sheath
• cerebroside, sulfatide, globoside, ganglioside
• also glycosphingolipids/ sphingoglycolipids

Question 11

oleic acid

Answer 11

MUFA

• olive oil
• 18C

Question 12

Cholesterol

Answer 12

• lipid raft
• ampipathic
• derived lipid

Question 13

Saturated FAs

Answer 13

• short chain, med and long chain

- no double bond

Question 14

palmitic acid

Answer 14

long chain saturated FA

-16 C

Question 15

steric acid

Answer 15

long chain saturated FA

• 18 C
• synth oleic acid

Question 16

what are the omega 6 FAs

Answer 16

• linoleic (C18) *essential 2 double bond

- arachidonic acid (C20)- 4 double bond – synth eicosanoids (proinflammatory)

Question 17

What are the omega-3 FAs

Answer 17

alpha linolenic acid (ALA) (C18) *essential, 3 double bond

• eicosapentanoic acid (EPA), (C20) 5 double bond (antiinflammatory, cardio protective)
• docasahexanoic acid (DHA) (C33) 6 double bond

Question 18

Which FAs have increased fluidity

Answer 18

arachidonic acid and docosahexanoic acid (DHA)

bc incr double bond

Question 19

cerebroside

Answer 19

glycosphingolipid

-ceramide + monosacch

Question 20

sulfatide

Answer 20

glycosphingolipid

-ceramide + monosacch + sulfate

Question 21

globoside

Answer 21

glycosphingolipid

-ceramide + oligosacch

Question 22

ganglioside

Answer 22

glycosphingolipid

-ceramide + oligosacch + NANA (9C sugar)