Lipoprotein issues

Question 1

Name the following for Type I hypercholesterolemia (hyperchylomicronemia):

• Defect
• Inheritance pattern
• Elevate lipid level
• s/sx or risks

Answer 1

• Lipoprotein lipase deficiency or altered C-II
• AR
• Chylomicrons, TG, cholesterol
• No increased risk for atherosclerosis
• Pancreatitis

Question 2

Name the following for Type IIa hypercholesterolemia (familial hypercholesterolemia):

• Defect
• Inheritance pattern
• Elevate lipid level
• s/sx or risks

Answer 2

• Absent or defective LDL receptors
• AD
• LDL, cholesterol increase
• Cholesterol deposits

Question 3

Name the following for Type IV hypercholesterolemia (hypertriglyceridemia):

• Defect
• Inheritance pattern
• Elevate lipid level
• s/sx or risks

Answer 3

• Hepatic overproduction of VLDL
• AD
• VLDL, TG
• Pancreatitis