What is pre hepatic jaundice?
Haemolytic anaemia
What is intra hepatic jaundice?
Problems with hepatocytes
What is post hepatic jaundice?
Obstruction of common bile duct
What is cholestasis?
Decrease in bile flow due to impaired secretion by hepatocytes
Where is bilirubin broken down?
Spleen
What is bilirubin bound to?
Albumin
Where does the bilirubin become conjugated?
Liver
What is conjugated bilirubin?
Water soluble
What is unconjugated bilirubin?
Lipid soluble
What does bilirubin bind to once in the liver?
Glucoronic acid
What does bilirubin change to once in the GI tract?
Urobilinigen