What is the largest gland in the body?
Liver
How heavy is the liver
1500 g or ~ 3 lbs.
Dimensions of the Liver
8” wide x 6.5” height x 4.5” deep
% of liver function needed for survival
10-20%
How many functions of the liver
over 500 functions
How many lobes in liver
4
Raw material for certain hormones and a building block for cell walls
Cholesterol
2 surfaces of the liver
diaphragmatic, visceral
aka liver cells
hepatocytes
little channels in the liver
canaliculi
liver organelle for storing sugar and regulation of blood glucose
glycosome
liver organelle that detoxifies blood-borne poisons
smooth ER
liver organelle that detoxifies other poisons like alcohol
peroxisomes
liver organelle that helps produce bile salts
smooth ER
liver organelle that is main energy source in hepatocytes
mitochondria
liver organelle that manufactures blood proteins
rough ER
location of liver in relation to diaphragm
Inferior to diaphragm in RUQ and epigastric area protected by ribs
mesentary binding liver to anterior abdominal wall
Falciform ligament
name the liver diseases discussed
Hepatitis (acute, viral, fulminant, chronic) alcoholic liver disease, alcoholic hepatitis, cirrhosis non-alcoholic hepatitis steatosis cholestatic liver disease (primary biliary cirrhosis, cholangitis) inherited disorders
organelles of the liver
rough ER, smooth ER, peroxisomes, golgi apparatus, mitochondria, glycosome
part not covered by peritoneum
bare area fused to diaphragm
regeneration of liver is through?
liver stem cells
serous membrane that lines the abdominal cavity; covers the liver
peritoneum
similar features with acute hepatitis but depicts more severe liver damage leads to a serious clinical state
acute liver failure