Local

Question 1

Allergic rxn to ester based local such as procaine is likely due to what component?

Answer 1

para-aminobenzoic acid

Question 2

what can be used for treatment of local anesthesia toxicity?

Answer 2

1-2ml/kg bolus or 0.2-0.5ml/kg/min infusion 20% lipid emlusion - egg yolk phospholipids, glycerin, water
this has been seen in animal studies; not FDA approved
standard tx for anesthetic-induced cardiac arrest is ACLS and cardiopulm bypass

Question 3

What is the maximum dose of lidocaine and epi in tumescence?

Answer 3

max of 55mg/kg of lidocaine (0.5-1gram/L), max dose of 0.055mg/kg of epi (1mg/L)

Question 4

What drug reverses the effects of epi in soft tissue?

Answer 4

subQ phentolamine