Local Toxicity

Question 1

Chloroprocaine

Ester

Answer 1

• Trade Name: Nesacaine
• Epi Conc: 3%
• Spinal Conc: 2%
• Max Dose: 12mg/kg
• Duration: 1/2-1 hr

Question 2

Procaine

Ester

Answer 2

• Trade Name: Novocaine
• Epi Conc: -
• Spinal Conc: -
• Max Dose: 12mg/kg
• Duration: 1/2-1 hr

Question 3

Tetracaine

Ester

Answer 3

• Trade Name: Pontocaine
• Epi Conc: -
• Spinal Conc: 1%
• Max Dose: 3mg/kg
• Duration: 1.5-6 hr

Question 4

Lidocaine

Amide

Answer 4

• Trade Name: Xylocaine
• Epi Conc: 2%
• Spinal Conc: 5%
• Max Dose: 4.5mg/kg
• Max Dose c̅ epi: 7mg/kg
• Duration: 0.75-1.5 hr

Question 5

Mepivicaine

Amide

Answer 5

• Trade Name: -
• Epi Conc: -
• Spinal Conc: -
• Max Dose: 4.5mg/kg
• Max Dose c̅ epi: 7mg/kg
• Duration: 1-2 hr

Question 6

Prilocaine

Amide

Answer 6

• Trade Name: Citanest
• Epi Conc: -
• Spinal Conc: -
• Max Dose: 6mg/kg
• Max Dose c̅ epi: 8mg/kg
• Duration: 0.5-1 hr

Question 7

Bupivacaine

Amide

Answer 7

• Trade Name: Marcaine
• Epi Conc: 0.1-0.125%
• Spinal Conc: 0.75%
• Max Dose: 2mg/kg
• Max Dose c̅ epi: 3mg/kg
• Duration: 1.5-8 hr

Question 8

Ropivacaine

Amide

Answer 8

• Trade Name: Naropin
• Epi Conc: 0.2%
• Spinal Conc: -
• Max Dose: 3mg/kg
• Max Dose c̅ epi: 3mg/kg
• Duration: 1.5-8 hr

Question 9

Intralipid 20%

Marcaine toxicity protocol

Answer 9

1.5-3 mL/kg
Max = 8mL/kg

Infusion rate: 0.25-0.5mL/kg/min