LQT Table

Question 1

INa

Long QT Type?

Answer 1

LQT3

Question 2

ICa-­‐L

Long QT Type?

Answer 2

LQT8

Question 3

IKr

Long QT Type?

Answer 3

LQT2,

LQT6 (α,β subunit defect)

Question 4

IKs

Long QT Type?

Answer 4

LQT1,

LQT5 (α,β subunit defect)

Question 5

IK1

Long QT Type?

Answer 5

LQT7

Question 6

INa

Effects?

Answer 6

Incomplete INa inactivation = increased excitation

Question 7

ICa-­‐L

Effects?

Answer 7

Incomplete ICa inactivation (Timothy

Syndrome)

Question 8

IKr

Effects?

Answer 8

Decreased K current =
inability to terminate plateau phase
and return membrane to resting potential

Question 9

IKs

Effects?

Answer 9

Decreased K current =
inability to terminate plateau phase
and return membrane to resting potential

Question 10

IK1

Effects?

Answer 10

Decreased K current during diastole