Questionnaires good for self-report with LBP (2)
2. Roland-Morris
Clinical progression of LBP (3 + time periods)
On/off switches at what three levels of the NS?
Gate control theory - “switch off”
at the spinal cord
non-nociceptive A-beta fibers recruit inhibitory neurons in the substantia gelatinosa of the posterior spinal cord
- chemically block ascending A-delta fibers and c-fibers
Four types of neurons in ascending pathways -
Spinal cord “switch on” with gate control theory
- theory of chronic spine pain
repetitious c-fiber firing thought to be enhanced by rapidly expressed genes => further increases sensitivity/sensitization of nociceptors = decreases threshold to stimulation and results in a wider receptor field
Brain stem “switch off”
stimulation of periaqueductal gray matter (PAG m.) by descending pathways from HIGHER centers
- PAG is opiodergic (descends to and affects the dorsal horn)
higher brain centers
Chemicals/agents released by higher brain centers for pain management
Dopamine
Serotonin
Endogenous opiates
Cannabinoids
Chemical responses from higher brain centers in presence of placebo, direct interventions, or both?
Clinical research has shown that both placebo and direct interventions may cause the release of multiple substances into the CNS in an opiodergic fashion
Subgroup for Targeted Treatment (STartT) Back Screening Tool
- use?
Promising tool to address homogeneity
Poor prognosticators for individuals with CLBP (2)
2. high disability
T or F: single red flag is predictive for serious dz
- if false, why?
False - many people have single red flags show up, but these should be used in clusters to lead the therapist to concerns for serious pathology - the higher the number of red flags, the greater the concern
T or F: nearly all pts will show one red flag w/o notable serious dz
- if false, why?
True
Two major serious dx to screen for in the outpatient setting
2. Undiagnosed fractures
Key clinical features of metastatic lesions (2)
2. overall clinician judgement
red flags of metastatic lesions (4)
red flags of undiagnosed vertebral fractures (CPR developed by Henschke and colleagues)
T or F: MRIs are good for identification of serious pathology
- if false, why?
True
T or F: MRIs are good for identifying painful stimulus agents in LBP of non-serious pathology
- if false, why?
False - good at finding abnormalities, but these abnormalities may not be the cause of the pt’s pain
- may lead to pt stress over patho label
T or F: MRIs may lead to lower levels of false positives regarding low back pain stimuli
False - MRIs can see a lot, but clinical research has shown that this may lead to more pathoanatomical “labels” which is not directly tied to a pt’s LBP
T2 weight vs T1 weighted MRIs
- visual difference between CSF
https://case.edu/med/neurology/NR/MRI%20Basics.htm
T1 - CSF is dark
T2 - CSF is light
Dark disk in T2
Thought to signs of DDD, but is usually benign and asymptomatic
- pt may hear “I have a deteriorating spine” and send them down a dark emotional path
What is Modic’s sign?