(M) Donor Selection

Question 1

familiarize the regulating agencies / accreditation

Answer 1

• CFR (code of federal regulations)
• CBER (Center for Biologics Evaluation and Research)
• AABB (American Association of Blood Banks)
• CMS (Centers for medicare and medicaid services)
• CLIA ‘88 (Clinical Laboratory Improvement Amendments of 1988)
• CAP (College of American Pathologists)

Question 2

Definition of terms

regular donation; collected blood use for transfusion of another patient or individual

Answer 2

allogeneic donation

Question 3

Definition of terms

The one who donates blood for his or her own use

Answer 3

Autologous Donation

Question 4

Definition of terms

Same with allogeneic but unit collected is directed towards a specific patient

Answer 4

Directed Donation

Question 5

Definition of Terms

Desired component of blood collected and centrifuged, and remaining elements subsequently returned to the donor

Answer 5

Apheresis Donation

Question 6

Steps in blood donation

Step 1 : Donor registration
1. ____ ID
2. Donor fills up the donor ____.
3. Should fully identify the donor & link the donor to existing ____.

Answer 6

1. Picture ID
2. donor fills up the donor form
3. Should fully identify the donor & link the donor to existing records

Question 7

Donor history questionnaire form

1. ____ personal information / data
2. Medical ____ questions
3. ____ awareness
4. Donor’s informed ____
5. Confidential Unit ____
6. ____ Examination
7. This can be ____ or by a trained donor historian

Answer 7

1. Donor personal information / data
2. Medical history questions
3. AIDS awareness
4. Donor’s informed consent
5. Confidential Unit exclusion
6. Physical Examination
7. This can be self administered or by a trained donor historian

Question 8

Step 2: Donor Selection & Screening
(enumerate the two steps)

Answer 8

a. Interview and Physical Examination
b. Pre-donation testing

Question 9

Step 2: Donor selection and screening

1. First Step in ensuring safety of our blood supply?
2. What are the two considerations?

Answer 9

1. Interview and physical exam
2. Safe for the donor and beneficial to the recipient

Question 10

Step 2: Donor Selection and Screening

Pre-donation counseling
1. ____ history assessment
2. knowledge of ____ and other ____
3. Donation information
4. ____ factor and knowledge

Answer 10

1. Risk history assessment
2. knowledge of HIV and other TTIs
3. Donation information
4. Psychosocial factor and knowledge

Question 11

Step 2: Donor selection and screening

1. Age limit for donors?
2. Temperature?
3. Pulse?

Answer 11

1. 16 years and above (no upper age limit)
2. ≤ 37.5 C
3. 50-100 bpm

Question 12

Step 2: Donor selection and screening

1. Weight
2. Hgb
   * Women
   * Men
3. Hct
   * Women
   * Men

Answer 12

1.equal to or more than 50 kg
2.Hgb
* Women : ≥ 12.5 g/dL
* men: ≥13 g/dL
3.Hct
* Women: ≥38%
* Men: ≥39%

Question 13

Hgb maximum values

Answer 13

• Women : 17.2 g/dL
• Men: 18.5 g/dL

Question 14

study the computation of the maximum draw for donors weighing less than the ideal weight (50kg)

Answer 14

Gaur

Question 15

Types of donor deferral

1. donor is unable to donate blood for a limited (specified) period of time
2. Donor will never be eligible to donate blood
3. Donor is unable to donate blood for an unspecified

Answer 15

1. Temporary deferral
2. Permanent deferral
3. Indefinite deferral

Question 16

Timing of donation or deferral

Antihistamine, Analgesic, Bronchodilators, Contraceptives, Decongestant, Food supplements, NSAID (except for platelet prep), Vitamins, Topical steroids

Answer 16

Anytime

Question 17

Timing of donation or deferral

Anticonvulsant, betablockers, digitalis, growth hormone, psoriasis treatment, Tegison / etretinate psychosis drugs, insulin

Answer 17

permanent

Question 18

Timing of donation or deferral

Antibiotic (after end of treatment), Proscar, Propecia, Acutane

Answer 18

one month

Question 19

Timing of donation or deferral

Dutasteride / avodart (BPH)

Answer 19

6 months

Question 20

Timing of donation or deferral

Anti-platelet activity
1. Feldene
2. Aspirin
3. Plavix / Ticlid

Answer 20

1. 2 days
2. 3 days
3. 14 days

Question 21

Timing of donation or deferral

1. Soriatane
2. Glutathione as prep for liver disorder
3. Glutathione for cosmetics use
4. Anti-hypertensive drugs

Answer 21

1. 3 years
2. permanent
3. 1 year
4. temporary (needs medical clearance)

Question 22

Timing of donation or deferral

1. COVID-19 Vaccine
2. Killed toxoids or synthetic viral / bacterial / rickettsial vaccine
3. Hepa A (non-exposure)
4. Hepa A (w/ close contact)

Answer 22

1. 14 days
2. No deferral (anytime)
3. Anytime
4. 6 weeks

Question 23

Timing of Donation / Deferral

1. Tetanus immunoglobulin
2. Rabies (post-exposure / bite)
3. Hepa B (non-exposure)
4. Hepa B (w/ close contact)

Answer 23

1. one year from last dose
2. one year from last dose
3. 1 week after vaccination
4. one year

Question 24

Timing of Donation / Deferral

1. Allogeneic whole blood donation (single unit)
2. Allogeneic whole blood donation (two units of RBC donation)

Answer 24

1. ≥ 8 weeks
2. ≥ 16 weeks

Question 25

# timing of Donation / Deferral Apheresis 1. platelet 2. Plasma (occasional) 3. Plasma (Serial) 4. Granulocyte 5. Double RBC autologous / allogenic

Answer 25

1. 48 hrs 2. 4 weeks 3. 48 hours 4. 48 hours 5. 16 weeks

Question 26

# Timing of donation / deferral 1. Pregnancy (existing / 6 weeks) 2. Pregnancy (miscarriage / abortion) 3. Malaria (lives in an endemic area) 4. Previously diagnosed with malaria (done with treatment, symptom-free) 5. History of travel from a malaria endemic area 6. Surgery, Blood transfusion, tooth extraction, tattoo, ear piercing, acupuncture, close contact w/ a person w/ hepatitis, incarcerated receipt of clotting factors

Answer 26

1. 6 weeks after delivery / 3 weeks after weaning 2. accept 3. 3 years 4. 3 years 5. 12 months 6. 12 months

Question 27

# Timing of donation / deferral based on HARMENING 1. CHD, CVD, RHD 2. Confirmed positive for HBsAg, anti-HBc, anti-HCV, HTLV 1/2, HIV 3. Cancer, leukemia, lymphoma 4. IV drug users 5. Blood diseases, hemophilia, SCA, kAPOSIS, Thalassemia, PCV

Answer 27

1. deffered ; if without disability may be accepted 2-5. Indefinite

Question 28

# Timing of donation / deferral based on the A-Z guide DOH 1. CHD, CVD, RHD 2. Confirmed positive for HBsAg, anti-HBc, anti-HCV, HTLV 1/2, HIV 3. Cancer, leukemia, lymphoma 4. IV drug users 5. Blood diseases, hemophilia, SCA, kAPOSIS, Thalassemia, PCV

Answer 28

1. PERMANENT 2. PERMANENT 3. PERMANENT 4. INDEFINITE 5. PERMANENT

Question 29

# Timing of donation / deferral based on HARMENING 1. Sexual contact with anyone with HIV/AIDS positive individuals 2. Female who had sex with men who had MSM 3. Treated for STD such as syphilis and gonorrhea

Answer 29

1. 12 months 2. 12 months 3. 12 months after completion of therapy

Question 30

# Timing of donation / deferral based on DOH 1. Sexual contact with anyone with HIV/AIDS positive individuals 2. . Female who had sex with men who had MSM 3. Treated for STD such as syphilis and gonorrhea

Answer 30

1. indefinite 2. indefinite 3. permanent

Question 31

# timing of donation / deferral based on HARMENING 1. MSM anytime since 1977 2. Casual sex, sex with IVD user, sex for money / drugs 3. From Central African Republig, Negeria, Chad, Congo, Gabon, Camerron

Answer 31

1. Permanent 2. Permanent 3. Indefinite

Question 32

# Timing of Donation / Deferral based on the A-Z guide (DOH) 1. MSM anytime since 1977 2. Casual sex, sex with IVD user, sex for money / drugs 3. From Central African Republig, Negeria, Chad, Congo, Gabon, Camerron

Answer 32

1-3. Indefinite

Question 33

# Step 2: Donor selection What are the two tests done during the pre-donation testing

Answer 33

1. ABO slide / tube method 2. Hemoglobin

Question 34

# Step 2: Donor Selection What are the two possible methods of hemoglobin testing for the pre-donation testing?

Answer 34

1. Copper sulfate 2. automated analyzer

Question 35

# Step 3: Donor phlebotomy 1. Use ____ technique * 70 % ____ alcohol * ____ compound

Answer 35

. Use **aseptic** technique * 70 % **isopropyl** alcohol * **Iodophor** compound

Question 36

# Step 3: Bleeding / phlebotomy 1. when do you label the blood bag 2. Ask donor to open and close hand every ____ seconds 3. Mix blood periodically every ____ seconds 4. Fill ____ tubes

Answer 36

1. during collection 2. 10-12 seconds 3. 45 seconds 4. pilot tubes

Question 37

# Step 3 : bleeding / phlebotomy 1. volume of a standard blood bag 2. low volume range for a 450 mL bag 3. low volume range for a 500 mL bag

Answer 37

1. 450 mL 2. 300 - 404 3. 333 - 449

Question 38

# Step 3: donor phlebotomy 1. tool used to mix blood from the segment with AC in the mother bag 2. tool used to keep a close system / hermetic seal

Answer 38

1. tube stripper 2. automatic tube sealer

Question 39

# ``` ``` What are included in the post donation screening?

Answer 39

1. ABO 2. Antibody

Question 40

What are the 5 TTIs

Answer 40

1. HIV 2. HEPA-B 3. HEPA-C 4. SYPHILIS 5. MALARIA

Question 41

Mild, severe, or moderate? 1. syncope 2. decreased pulse 3. hyperventilation 4. vasovagal syncope 5. Twitching / muscle spasm

Answer 41

1. mild 2. moderate 3. moderate 4. severe 5. mild

Question 42

Mild, Moderate, Severe? 1. loss of consciousness 2. shock 3. marked hyperventilation 4. Vomitting 5. fall in systolic bp

Answer 42

1. mild 2. severe 3. severe 4. mild 5. moderate

Question 43

# Matching type 1. Weakness, sweating dizziness, pallor, nausea and vomiting 2. syncope 3. twitching, muscle spasm a. cold compress on back of neck b. Remove needle and tourniquet, elevate legs above head, apply cold compress to forhead and back of neck c. have donor cough

Answer 43

1. b 2. a 3. c

Question 44

# Maching type 1. Convulsion 2. Hematoma 3. Cardiac difficulties a. apply pressure for 7-10 minutes, apply ice to area for 5 minutes b. begin cardiopulmonary resuscitation, call for help emergency c. call for help, prevent donor from falling from donor chair to prevent injury, ensure donor's airway is adequate

Answer 44

1. C 2. A 3. B

Question 45

# AUTOLOGOUS DONATION familiarize the 4 collections

Answer 45

1. preoperative collection 2. acute normovolemic hemodilution 3. intraoperative collection 4. postoperative collection

Question 46

# Autologous donation Preoperative collection 1. Hgb = 2. Hct = 3. Last donation must be within ____ hrs before surgery 4.ABO Rh is (required / not required) 5. Distinct label = 6. TTI is only if to be transfused ____ the collecting facility

Answer 46

Preoperative collection 1. Hgb = **11 g/dl** 2. Hct = **33%** 3. Last donation must be within **72** hrs before surgery 4. ABO Rh is **mandatory** 5. Distinct label = **for autologous use only** 6. TTI is only if to be transfused **outside** the collecting facility

Question 47

# Autologous Donation Acute normovolemic hemodilution (ANH) 1. WB is removed, replaced with ____ / colloid before surgical blood loss 2. Indication = 3. Label = 4. Storage: ____ hrs RT ; 24 hrs ____C 5. Reinfusion (shed blood) is done on ____ order. last unit with the highest HCT

Answer 47

1. WB is removed, replaced with **crystalloids** / colloid before surgical blood loss 2. Indication : **surgical blood loss** 3. Label = **For autologous use only** 4. Storage: **8** hrs RT ; 24 hrs **1-6C** 5. Reinfusion (shed blood) is done on **reverse** order. last unit with the highest HCT

Question 48

# Autologous donation Intraoperative collection 1. collecting and reinfusing blood lost during ____ 2. Indication: cardiac, cardiothoracic, vascular major orthopedic surgery 3. Label: 4. Storage : ____ hrs RT; 24 hrs ____C 5. Risk =

Answer 48

1. collecting and reinfusing blood lost during **surgery** 2. Indication: cardiac, cardiothoracic, vascular major orthopedic surgery 3. Label: **for autologous use only** 4. Storage : **6** hrs RT; 24 hrs **1-6**C 5. Risk = **DIC**

Question 49

# Autologous donation Post operative blood collection 1. blood is collected from a drainage tube at the ____ 2. Indication: 3. Storage : ____ hrs RT; 24 hrs ____ 4. Reinfused without processing; volume no more than ____

Answer 49

1. blood is collected from a drainage tube at the **surgical site** 2. Indication: c**ardiac and orthopedic surgery** 3. Storage : **6** hrs RT; 24 hrs **1-6C** 4. Reinfused without processing; volume no more than **1400 mL**

Question 50

# Step 4: post donation processing What are the four components?

Answer 50

1. whole blood / red cell components 2. platelet concentrate 3. Fresh Frozen plasma 4. cryoprecipitate

Question 51

Arrange the following from the first to the last step a. Post-donation care b. Donor selection and screening c. Donor Phlebotomy d. Donor Registration

Answer 51

d, b, c, a