Macrolides

Question 1

Macrolides

Answer 1

erythromycin, azithromycin, telithromycin, clarithromycin, fidaxomycin, cethromycin

Question 2

MOA

Answer 2

inhibit bacterial protein synthesis at 50s ribosomal subunit

Question 3

Spectrum

Answer 3

not strep pneumo! Gram (+) staph and strep, corynebacteria, mycoplasma, legionella, listeria. Gram (-) neissaria, bordetella, bartonella, treponema, campylobacter, H. pylori, H. flu

Question 4

Indications

Answer 4

respiratory, AOM, strep pharyngitis, SSTI, Chlamydia, pertussus, diptheria, GI,

Question 5

ADR

Answer 5

Long QT, stevens-johnson syndrome, TEN