Macrolides DI

Question 1

Macrolides

Answer 1

Erythromycin, clarithromycin, azithromycin

Question 2

Macrolides MoA

Answer 2

Reversibly bind to the 50S ribosomal subunit to inhibit bacterial protein synthesis

Question 3

Are macrolides bacteriostatic or bacterialcidal?

Answer 3

Bacteriostatic

Question 4

Macrolides spectrum of activity

Answer 4

+++ against gram-positive aerobes, also active against atypicals

Question 5

Macrolides side effects

Answer 5

GI intolerance, phlebitis with IV erythromycin

Question 6

Macrolides are the choice drug in what type of infection?

Answer 6

CAP