Examples
Erythromycin
Clarithromycin
Azithromycin
MoA
50s subunit of bacterial ribosome
Antagonist
Prevents translocation of growing peptide chain
Inhibits bacterial synthesis
Indications
ALTERNATIVE TO PENICILLIN
Pneumonia
ADR
GI upset
Hypersensitivity reaction
QT Prolongation
Prescribing Advice
Inhibits metabolism of Ciclosporin/Theophylline
CYP450 inhibitor