ANTIBIOTICOS > Macrolidos > Flashcards

Macrolidos Flashcards

(6 cards)

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1
Q

Macrolidos

A

Eritromicina, Claritomicina, Azitromicina, Telitromicina

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2
Q

MA

A

bacteriostático y bactericida
Inh 50S, peptidil trasferasa (inh. translocación)

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3
Q

Espectro

A

+ gramp y negativos, atípicos
Strep pyogenes, neumococos, clamidia, M. pneumoniae, legionella, mycobacterium, H. pylori

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4
Q

Indicaciones generales

A

Tx para infecciones respiratorias (sinusitis, otitis media, faringitis, bronquitis, neumon. extrahospitalaria)
1° elección para bordatella pertussis (tos ferrina)

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5
Q

ADME

A

inhibición potente de CYP3A4
buena distribución

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6
Q

EA

A

bastantes seguros
estomatitis, pirosis, náusea, anorecia, dolor abdominal, diarrea

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