Protein
Large molecule (polymer) consisting of many amino acid subunits (monomers), joined by peptide bonds folded into a 3D shape
Amino acid
Molecule (monomer) containing a carboxyl group and amino group and hydrogen atom attached to a central carbon atom
How many amino acids and how to distinguish
20 different, the functional groups distinguish which one, can be polar or nonpolar
How are the 20 amino acids consumed
12 are synthesized by cells, 8 need to be consumed by diet
Peptide bond
Covalent bond linking amino acids by dehydration synthesis. Occurs between the NH2 of an amino acid and the COOH of the second amino acid
Peptide, dipeptides, oligopeptides, polypeptides
Peptide - chain on amino acid subunits that are connected by peptide bonds.
Di- 2
Olgio - 3-10
Poly - 10+
Primary structure
Unique linear sequence of AAs in peptide chain
Secondary structure
3D arrangement caused by hydrogen bonding at regular intervals
Tertiary Structure
3D folding pattern of a protein due to side chain interactions
Quaternary structure
2 or more polypeptide chains linked together into a single protein
Nucleic acids
Blueprint for proteins that are synthesized in cells and stores hereditary info
Sends info from DNA to RNA to synthesize proteins
DNA
stores hereditary info responsible for inherited traits in all eukaryotes and prokaryotes and many viruses
Eukaryotes - membrane bound nucleus
Prokaryotes - no membrwne
RNA
hereditary molecule in some viruses invoked in protein synthesis in all cells
Nucleotides
Monomers of nucleic acids, made of a nitrogenous base formed from rings of carbon and nitrogen atoms, 5 carbon ring shaped sugar, 1-3 phosphate groups
What do the phosphate groups in RNA do
They’re the energy source of nucleotides
Pyrimidine vs purines
Pyrimidine = single organic rings (Uracil, Thymine, Cytosine)
Purines = two ringed organic structure
(Adenine, Guanine)
Phosphodiester bond
Link formed between nucleotides linking between the 5 carbon of one sugar and the 3 carbon of the next sugar
Forms backbone of chain
Builds in one direction
Characteristics of DNA
deoxyribose, phosphate group and one of the 4 bases (A C T G)
Double stranded molecule that runs antiparallel
Hydrogen bonds hold the strands together
How many bonds for guanine to bond to cytosine and adenine to thymine
G - C = 3
A - T = 2
RNA characteristics
Ribose, phosphate group, one of the four bases (A C G U)
single stranded molecule
No hydrogen bonds hold
carbohydrate composition
carbon, hydrogen, oxygen
carb main functions
structure, energy, cell to cell communication, building blocks for other macros
monosaccharides
simplest form of carb
single sugar unit
monosaccharides containing 3,5,6 carbons are the most common (triose,pentose,hexose)