Malignant Hyperthermia

Question 2

List triggers for MH.

Answer 2

Volatile Anesthetics & SCh

Question 3

List signs of MH crisis

Answer 3

1. tachycardia
2. rapidly increasing ETCO2
3. skin mottling
4. tachypnea
5. increase in temp

Question 4

List the treatment regimen for MH.

Answer 4

1. STOP THE TRIGGER
2. 100% O2 hyperventilation
3. Dantrolene 2.5mg/kg IV (repeat 5-10mins; MAX 10mg/kg)
4. Actively cool pt
5. correct hyperkalmia and metabolic acidosis
6. Monitor labs and maintain UO >2cc/kg/hr (hydration, mannitol, lasix) watch for rhabdo

Question 5

What is the dose of Dantrolene for MH?

Answer 5

2.5mg/kg IV (repeat q5-10mins prn)

MAX 10mg/kg