May 18th

Question 1

Asterixis can be seen in what states?

Answer 1

Hepatic encephalopathy, uremic encephalopathy, and CO2 retention

Question 2

What exam maneuver can be helpful in distinguish benign pathologic murmurs in children?

Answer 2

Sitting/standing (decreasing preload) reduces the intensity of a benign murmur; if it increased with standing or valsalva it would be pathologic

Question 3

What are the lab findings of Paget disease of the bone?

Answer 3

Elevated alk phosphatase, elevated PINP and urine hydroxyproline, calcium and phos usually normal

Question 4

What is een on MRI in Alzheimer disease?

Answer 4

Temporal and parietal lobe atrophy

Question 5

What is the genetic inheritance of Hyper-IgM syndrome?

Answer 5

X linked defect in CD40 ligand (on T cells)