Which cells are required for an adaptive immune response?
Lymphocytes
MHC Class I presents peptides of what length to CD8T cells?
8-10 aa
Which pathogens do T helper 2 (Th2) cells primarily provide cell-mediated immunity against?
Helminths and extracellular parasites
Where are peptides for MHC class I presentation generated?
Proteasomes
How does the IglC protein contribute to virulence of Francisella tularensis?
it is required to induce apoptosis of infected macrophages
Which property is associated with Francisella tularensis?
It inhibits the macrophage respiratory burst
Which component of the Burkholderia pseudomallei bacterial cell protects the organism from complement activation?
Capsular polysaccharide
Which virulence factor of Helicobacter pylori disrupts the gastric mucin layer?
urease
What makes lysozyme antimicrobial?
Targets the cell wall peptidoglycan
How can virus-antibody complexes contribute to disease development?
By enhancing viral uptake into cells via Fc receptors
Why is the M2e region of the M2 protein a target for new influenza vaccine approaches?
It has remained highly conserved since 1918
What is the role of protein kinase R (PKR) in the antiviral state?
PKR phosphorylates eIF2a to inhibit protein synthesis
Which PAMP does Toll-like receptor 7 (TLR-7) recognise?
Single-stranded RNA
