What are some advantages and disadvantages of single appointments (obturation without using medicaments?)
Advantage
Disadvantage:
What are some advantages with using medicaments?
What factors should be considered when deciding whether to medicate?
How does biofilm grow? Why can antibiotics not remove root canal infection?
Adsorption of proteins to surface
Adhesion and cohesion of bacteria to each other and protein
Growth and metabolism of bacteria
As biofilm grows clumps get detached and travel to more distant sites
Properties:
Grow slowly, infection slow to produce overt symptoms
Antibiotics may relieve symptoms, but can not remove infection as can not access root canal space (same goes with host defence)
Therefore, once stop antibiotics can cause recurrent infection
What are the ideal properties of medicaments?
Tissue effects:
Effectiveness
Operator + pt factors
What medicaments should be used for:
How should medicaments be delivered?
What are the properties of CaOH and how does it worK? How long should it be left in the mouth?
Properties:
-Bactericidal (pH 12.2)
Induces calcification by causing cell necrosis→ activates alkaline phosphatase→ calcific bridge formation)
-Promotes periapical healing (buffers acid prodcued in inflammatory fluids)
-Dissovles necrotic tissue
Inactivates endotoxin
pH decreases as get further out from main canal
-Effectiveness buffered/reduced by dentine + intracellular pH regulation (e.g. proton pump)
What are the properties of chlorhexidine?
-Antimicrobial effects for 12 weeks
-Tends to be more effective antimicrobial than CaOH2 but no statistical significance
-Does not dissolve tissue
Less effective vs gram negative than gram positive bacteria
-Effectiveness reduced in presence of dentine powder and protein (like most other antimicrobial agents)
-Not in readily available formulation for endo
What does odontopaste contain? Does it cause discoloration?