class of carbamazepine
TCA
carbamezipine commonly used where
epilepsy - partial seizures
trigeminal neuralgia
bipolar disorder
MOA of carbamazepine
binds to sodium channels increases their refractory period
adverse effects of carbamazepine
P450 enzyme inducer dizziness and ataxia drowsiness headache visual disturbances (especially diplopia) Steven-Johnson syndrome leucopenia and agranulocytosis hyponatraemia secondary to syndrome of inappropriate ADH secretion
why do pts see a return of seizures after 3 - 4 weeks of treatment
exhibit autoinduction