Clozapine (Clozaril)
a medication used to treat mood disorders such as schizophrenia and schizoaffective disorder. A last resort medication.
Clozapine uses
Used to treat positive symptoms, mood, and lowers risk of suicide
Side effects of Clozapine
less chance of developing EPS but high chance of agranulocytosis.
Labs to monitor
WBC, ANC. Monitor weekly for the first six months, bi-weekly for the 6 months remaining, and then monthly for the following
Lithium
a medication used to treat mood disorders. (mood stabilizer)
Ranges for lithium
1-1.5 (acute manic phase)
Lithium toxicity ranges for mild-moderate
1.5-2
Lithium toxicity ranges for moderate-severe
2+
Most severe adverse reaction to Lithium
cardiac dysrhythmias
Prior to lithium which levels do you need to obtain
renal, cardiac, and thyroid function
Where is lithium excreted
kidneys and the liver does not play a role
Antiparkinsonian agents
levodopa carbidopa (dopamine agonist), MAOI (seligence), COMT inhibitors (entacapome), Benzotropine (cogentin), antiviral (amantadine), bendaryl (anthistamine)
Anitdepressant education